|
|
-
Staudt M., Buro-Auriemma L., Walters M., Salit J., Vincent T., Shaykhiev R, Mezey J., Tilley
A., Kaner R., Ho M., Crystal R. 2014. Airway basal stem / progenitor cells have diminished capacity to regenate airway epithelium in chronic obstructive pulmonary disease. American Journal
of Respiratory and Critical Care Medicine 190:955-958. PMID: 25317467.
-
Walters M., De B., Salit J., Buro-Auriemma L., Wilson T., Rogalski A., Lief L., Hackett
N., Staudt M., Tilley A. Harvey B., Kaner R., Mezey J., Ashbridge B., Moore M., Crystal R. 2014.
Smoking accelerates aging of the small airway epithelium. Respiratory Research 15:94, PMID
25248511.
-
Lis R, Touboul C, Halabi N, Madduri A, Querleu D, Mezey J., Malek J, Suhre K, Rafii A.
2014. Mesenchymal cell interaction with ovarian cancer cells induces a background dependent prometastatic transcriptomic profle.
Journal of Translational Medicine 12:59, PMID: 24597747.
-
Ryan D, Vincent T, Salit J, Walters M, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y,
Downey R, Buro-Auriemma L, Staudt M, Hackett N, Mezey J., Crystal R. 2014. Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2. PLoS ONE
9:e88051, PubMed PMID: 24498427.
-
Reardon B., Hansen J., Crystal R., Houston D., Kritchevsky S., Harris T., Lohman K., Liu
Y., O'Connor G., Wilk J., Mezey J., Gao C., Cassano P. 2013 Vitamin D-responsive SGPP2 variants associated with lung cell expression and lung function. BMC Medical Genetics 14:122,
PMID: 24274704.
-
Abou Ziki M., Strulovici-Barel Y., Hackett N., Rodriguez-Flores J., Mezey J., Salit J., Radisch
S., Hollmann C., Chouchane L., Malek J., Zirie M., Jayyuosi A., Gotto A., Crystal R. 2014 Prevalence of the Apolipoprotein E Arg145Cys Dyslipidemia At-Risk Polymorphism in African-Derived
Populations. American Journal of Cardiology 113:302-308, PMID: 24239320.
-
Goldstein O., Mezey J., Schweitzer P., Boyko A., Gao C., Bustamante C., Jordan J., Aguirre
G., Acland G. 2013 IQCB1 and PDE6B mutations cause similar early onset retinal degenerations
in two closely related terrier dog breeds. Investigative Opthalmology and Visual Science
54:7005-7019, PMID: 24045995.
-
Harvey B., Strulovici-Barel Y., Vincent T., Mezey J., Raviram R., Gordon C., Salit J., Tilley
A., Chung A., Sanders A., Crystal R. 2013 High correlation of the response of upper and lower lobe
small airway epithelium to smoking. PLoS One 8:e72669, PMID: 24039793.
-
Orlin A., Sondhi D., Witmer M., Wessel M., Mezey J., Kaminsky S., Hackett N., Yohay K.,
Kosofsky B., Souweidane M., Kaplitt M., D'Amico D., Crystal R., Kiss S. 2013 Spectrum of ocular
manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing
age and deteriorating neurological function. PLoS One 8:e73128, PMID: 24015292.
-
Agler A., Crystal R., Mezey J., Fuller J., Gao C., Hansen J., Cassano P. 2013 Differential
expression of vitamin e and selenium-responsive genes by disease severity in chronic obstructive
pulmonary disease. COPD 10:450-458, PMID: 23875740.
-
Kaminsky S., Quach L., Chen S., Pierre-Destine L., Van de Graaf B., Monette S., Rosenberg
J., De B., Sondhi D., Hackett N., Mezey J. , Rosengart T., Crystal R. 2013. Safety of direct cardiac administration of AdVEGF-All6A+, a replication-defcient adenovirus vector cDNA/genomic
hybrid expressing all three major isoforms of human Vascular Endothelial Growth Factor, to the
Ischemic Myocardium of Rats. Human Gene Therapy Clinical Development 24:38-46, PMID:
23692382.
-
Fukui T., Shaykhiev R., Agosto-Perez F., Mezey J. , Downey R., Travis W., Crystal R. 2013.
Lung adenocarcinoma subtypes based on expression of human airway basal cell genes. European
Respiratory Journal 42:1332-1344, PMID: 23645403.
-
Brisbin A., Bryc K., Byrnes J., Zakharia F., Omberg L., Degenhardt J., Reynolds A., Ostrer H., Mezey J., Bustamante CD. 2012 PCAdmix: principal components-based assignment of
ancestry along each chromosome in individuals with admixed ancestry from two or more populations. Human Biology 84:343-364, PMID: 23249312.
-
Wang R., Ahmed J., Wang G., Hassan I., Strulovici-Barel Y., Salit J., Mezey J., Crystal R.
2012 Airway epithelial expression of TLR5 is down regulated in healthy smokers and smokers with
chronic obstructive pulmonary disease. The Journal of Immunology 189:2217-2225, PMID:
22855713.
-
Makvandi-Nejad S., Hoffman G., Allen J., Chu E., Gu E., Chandler A., Loredo A., Bellone
R. Mezey J., Brooks S., Sutter N. 2012. Four loci explain 83% of size variation in the horse. PloS
One 7: e39929, PMID 22808074.
-
Wang G., Xu Z., Wang R. Ai-Hijji M., Salit J., Stulovici-Barel Y., Tilley A., Mezey J., Crystal
G. 2012. Genes associated with MUCAC expression in small airway epithelium of human smokers
and non-smokers. BMC Medical Genomics 5:21, PMID 22676183.
-
Jarvis J., Scheinfeldt L., Soi S., Lambert C., Omberg L., Ferwerda B., Bodo J-M., Beggs
W., Hoffman G., Mezey J., Tishkoff S. 2012. Signatures of natural selection and genetic association
with stature in west African pygmies. PLoS Genetics 8:e1002641, PMID: 22570615.
-
Rosenberg J., Hicks M., De B., Pagovich O., Frenk E., Janda K., Wee S., Koob G., Hackett N.,
Kaminsky S., Worgall S., Tignor N., Mezey J., Crystal R. 2012. AAVrh.10-mediated expression of
an anti-cocaine antibody mediates persistent passive immunization that suppresses cocaine-induced
behavior. Human Gene Therapy 23:451, PMID: 22486244.
-
Hackett N., Butler M., Shaykhiev R., Salit J., Omberg L., Rodriguez-Flores J., Mezey J.,
Strulovici-Barel Y., Wang G., Didon L., Crystal R. 2012. RNA-Seq quantification of the human
small airway epithelium transcriptome. BMC Genomics 13:82, PMID 22375630.
-
Zhao K., Tung C-W., Wright M., Eizenga G., McClung A., Price A., Mezey J., Reynolds
A., Liakat A., Bustamante C., McCouch S. 2011. Genome-wide association mapping of complex
traits in rice. Nature Communications 2:467, PMID: 21915109.
-
Tilley A., O'Connor T., Hackett N., Strulovici-Barel Y., Salit J., Amoroso N., Zhou K., Raman
T., Clark A., Mezey J., Crystal R. 2011. Biologic categorization of healthy nonsmokers, healthy
smokers and smokers with COPD based on the transcriptome of the small airway epithelium. PLoS
One 6:e22798, PMID: 21829517.
-
Mao, Y., Kiss S., Hackett N., Qiu J., Carbone A., Mezey J., Kaminsky S., D'Amico D., Crystal
R., 2011. Persistent suppression of ocular neovascularization with intravitreal administration of
AAVrh.10 coding for bevacizumab. Human Gene Therapy 22:1525-1535, PMID: 21801028.
-Featured article in Human Gene Therapy
-
Godron C., Gudi K., Krause A., Sackrowitz R., Harvey B-G, Strulovici-Barel Y., Mezey J.,
Crystal R. 2011. Circulating endothelial microparticles as a measure of early lung destruction in
cigarette smokers. American Journal of Respiratory and Critical Care Medicine 184:224-232, PMID: 21471087.
- Editorial article in Am J Respir Crit Care Med. 184:154-155: Endothelial Chronic Destructive Pulmonary Disease (E-CDPD): Is Endothelial Apoptosis a Subphenotype or Prequel to COPD?.
-
Butler M., Hackett N., Salit J., Strulovici-Barel Y., Omberg L., Mezey J., Crystal R. 2011.
Glutathione S-transferase copy number variation alters lung gene expression. European Respiratory Journal 38:15-28, PMID: 21349909.
-
Butler M., Fukui T, Salit J., Shaykhiev R., Mezey J., Hackett N., Crystal R. 2010. Modu-
lation of Cystatin A expression in the human small airway epithelium by genotype, smoking, and
COPD. Cancer Research 71:2572-2581, PMID: 21325429.
-
Hicks M., De B., Rosenberg J., Davidson J., Moreno A., Janda K., Wee S., Koob G., Hackett
N., Kaminsky S., Worgall S., Toth M., Mezey J., Crystal R. 2010. Cocaine analog conjugated to
disrupted E1-E3- adenovirus - a small molecule / viral protein vaccine strategy to evoke high-titer
immunity against non-immunogenic addictive drugs. Molecular Therapy 19:612-619, PMID:
21206484.
- Press coverage in Bloomberg (online), CNN (online), Time (online), and others; Mezey second
senior author.
-
Goldstein O., Mezey J., Boyko A., Gao C., Wang W., Bustamante C., Anguish L., Jordan
J., Pearce-Kelling S., Aguirre G., Acland G. 2010. ADAM9 mutation in canine cone-rod dystropy
3 (crd3) establishes homology with human CORD9. Molecular Vision 16:1549-1569, PMID:
20806078.
-
Strulovici-Barel Y., Omberg L., O'Mahony M., Gordon C., Hollman C., Tilley A., Salit J.,
Mezey J., Harvey B.-G., Crystal R. 2010. Threshold of biologic response of the small airway
epithelium to low levels of tobacco smoke. American Journal of Respiratory and Critical Care
Medicine 182:1524-1532, PMID: 20693378.
- Press coverage in Time (online), LA Times (online), US News and World Report (online),
MSN.com, CNN.com and others; my postdoc L. Omberg is co-first author.
-
Turetz M., O'Connor T., Tilley A., Strulovici-Barel Y., Salit J., Dang D., Teater M., Mezey J.,
Clark A., Crystal R. 2010. The trachea epithelium as a canary for cigarette smoking-induced biologic
phenotype of the small airway epithelium. Clinical and Translational Science 2:260-272,
PMID: 20443905.
-
Brooks, S., Gabreski, N., Miller, D., Brisbin, A., Brown, H., Streeter, C., Mezey J., Antczak,
D. 2010. Whole genome SNP association in the horse: identification of a deletion in myosin va
responsible for lavender foal syndrome using the equine SNP50 genotyping platform. PLoS Genetics 6:e1000909, PMID: 20419149.
-
Brooks M., Etter K., Catalfano J., Bustamante C., Mezey J. 2010. A genome-wide linkage
scan in German shepherd dogs localizes canine platelet procoagulant deficiency (Scott Syndrome)
to canine chromosome 27. Gene 450:70-75, PMID: 19854246.
-
Hubner R., Schwartz P., Bishnu P., Ferris B., Omberg L., Mezey J., Hackett N., Crystal R.
2009. Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium
highly responsive to cigarette smoking. Molecular Medicine 15:203-219, PMID: 19593404.
- Featured article in Molecular Medicine podcast.
-
Casey B., Glatt C., Tottenham N., Soliman F., Bath K., Amso D., Altemus M., Pattwell
S., Jones, R. Levita L., McEwen B., Magarinos A., Gunnar M., Thomas K., Mezey J., Clark A.,
Hempstead B., Lee F. 2009. BDNF as a model system for examining gene by environment interactions
across development. Neuroscience 164:108-120, PMID: 19358879.
-
Castelhano M., Acland G, Ciccone P., Corey E., Mezey J., Page R., Schimenti J. Todhunter R.
2009. Development and use of DNA archives at veterinary teaching hospital to investigate the
genetic basis of disease. Journal of the American Veterinary Medical Association 234:75-80,
PMID: 19119968.
-
Mezey J., Nuzhdin S., Ye F., Jones C. 2008. Coordinated evolution of co-expressed gene
clusters in the Drosophila transcriptome. BMC Evolutionary Biology 8:2, PMID: 18179715.
-
Holloway A., Lawniczak M., Mezey J., Begun D., Jones C. 2007. Adaptive gene expression
divergence inferred from population genomics. PLoS Genetics 3:2007-2013, PMID: 17967066.
-
Kim T-S., Logsdon B., Park S., Mezey J., Lee K.. 2007. Quantitative trait loci for circadian
clock identified in Neurospora crassa. Genetics 177:2335-2347, PMID: 17947430 .
-
Zelditch M., Mezey J., Sheets H., Lundrigan B., Garland T. 2006. Developmental regulation of
skull morphology II: ontogenetic dynamics of covariance. Evolution and Development
8:46-60, PMID: 16409382.
-
Mezey J. 2006. Modularity. Fox, C.W. and J.B. Wolf (eds.) Evolutionary Genetics: Concepts and Case Studies. Oxford University Press.
-
Mezey J., Houle D. 2005. The dimensionality of genetic variation for wing shape in Drosophila
melanogaster. Evolution 59:1027-1038, PMID: 16136802.
-
Hahn M., Mezey J., Begun D., Gillespie J., Kern A., Langley C., Moyle L. 2005.
Evolutionary genomics: codon bias and selection on single genomes. Nature 433:E5, PMID: 15662370.
-
Mezey J., Houle D., Nuzhdin S. 2005. Naturally segregating QTL affecting wing shape of
Drosophila melanogaster. Genetics 169:2101-2113, PMID: 15520257.
-
Wagner G., Mezey J., Callabretta R. 2005. Natural selection and the origin of modules.
W. Callebaut and D. Rasking-Gutman (eds.) Modularity: Understanding the Development and
Evolution of Natural Complex Systems. MIT Press.
-
Wagner G., Mezey J. 2004. The role of genetic architecture constraints for the origin of
variational modularity. G. Schlosser and G.P. Wagner (eds.) Modularity in Development and Evolution. Chicago University Press.
-
James F., Mezey J. 2004. Geographic variation in the size and shape of the Savannah Sparrows
(Passerculus sandwichensis). The Auk 121:269-270.
-
Houle D., Mezey J., Galpern P., Carter A. 2003. Automated measurement of Drosophila
wings. BMC Evolutionary Biology 3:25, PMID: 14670094.
-
Mezey J., Houle D. 2003. Comparing G matrices: are common principal components informative? Genetics 165:411-425, PMID: 14504246.
-
Houle D., Mezey J., Galpern P. 2002. Interpretation of the results of partial common principal
components. Evolution 56:433-440, PMID: 11989675.
-
Housworth E., Mezey J., Cheverud J., Wagner G. 2001. The test distribution of modularity statistics:
a correction and clarification. Genetics 158:1381, PMID: 11478289.
-
Mezey J., Cheverud, J. Wagner G. 2000. Is the genotype-phenotype map modular? An
approach using quantitative trait locus (QTL) data. Genetics 156:305-311, PMID: 10978294.
-
Wagner G., Mezey J. 2000. Modeling the evolution of genetic architecture: a continuum of
alleles model with pairwise AxA epistasis. Journal of Theoretical Biology 203:163-175, PMID:
10704300.
-
Mezey J., Wagner G. 2000. An effect of scale in a non-additive genetic model. Y. Bar-Yam
(ed.) Unifying Themes in Complex Systems: Proceedings of the First International Conference on
Complex Systems. Perseus Books Group.
-
Kim C., Kawasaki K., Minoshima S., Amemiya C., Miller W., Shimizu N., Bailey W., Wagner
G., Mezey J., Ruddle F. 2000. Hox cluster duplication in the horn shark (Heterodontus francisi) and
the vertebrate radiation. Proceedings of the National Academy of Sciences 97:1655-1660,
PMID: 10677514.
|
|
|
|
|