Research Group

  • McCouch S., Wright M., Tung C-W., Maron L., McNally K., Fitzgerald M., Singh N., DeClerck G., Agosto-Perez F., Korniliev P., Greenberg A., Naredo M., Mercado S., Harington S., Shi Y., Branchini A., Kuser-Falcao, P., Leung, Ebana K., Yano M., Eizenga G., McClung A., Mezey J. The power of population-specific genome-wide association study (GWAS) mapping in rice (Orzya saliva) with an open access resource. Nature Communications 7:10532 PMID: 26842267.

  • Rodriguez-Flores J., Fakhro K., Agosto-Perez F., Vincent T., Robay A., Malek J., Suhre K., Chouchane L., Badii R., Al-Marri A., Khalil C., Zirie M., Jayyousi A., Salit J., Clark A., Crystal R., Mezey J. Indigenous arabians are descendants of the earliest split from ancient eurasian populations. Genome Research 26:151-162 PMID: 26728717. - Genome Research Feb 2016 Cover - Press coverage in Genome Web, Genome Top News, Phys.org, and others

  • Hoffman G., Mezey J., Schadt E., 2014. lrgpr: Interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R. Bioinformatics 30:3134-3135 PMID: 25035399.

  • Gao C., Tignor, N., Salit J., Strulovici-Barel Y., Hackett N., Crystal R., Mezey J. 2014. HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors. Bioinformatics 30:369-376 PMID: 24307700.

  • Hoffman G. 2013. Correcting for population stratification using principal components or a linear mixed model: a unified framwork and its implications. PLoS One 8:e75707, PMID 24204578.

  • Rodriguez-Flores J., Fakhro K., Hackett N., Salit J., Fuller J., Agosto-Perez F., Gharbiah M., Malek J., Zirie M., Jayyoussi A., Badii R., Al Marri A., Chouchane L., Stadler D, Mezey J.*, Crystal R.* 2014. Exome sequencing of the qatari population identifies unique risks for mendelian disorders. Human Mutation 35:105-116, PMID 24123366. - *Co-senior authors

  • Mahdi R., Mezey J. 2013. Sub-local constraint-based learning of Bayesian networks with a mutual dependence criterion. Journal of Machine Learning Research 14:1563-1603.

  • Hoffman G., Logsdon B., Mezey J. 2013. PUMA: a unified framework for penalized regression analysis of GWAS data. PLoS Computational Biology 7:e1003101, PMID: 23825936.

  • Rodriguez-Flores J., Salit J., Fuller J., Omberg, L. Hackett R., Malek J., Crystal R., Mezey J. 2012 Exome of only seven qataris identifies potentially deleterious variants in the qatari population. PLoS One 7:e47614, PMID: 23139751.

  • Omberg L., Salit, J., Hackett N., Fuller J., Matthew R., Chouchane L., Rodriguez-Flores J., Bustamante C., Crystal G., Mezey J. 2012. Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations. BMC Genetics 13:49, PMID: 22734698. - Selected as an Editor's pick and designated as highly accessed by BMC Genetics

  • Mahdi R., Wang, G., Strulovici-Barel Y., Salit J., Hackett N., Crystal R., Mezey J. 2012. Empirical Bayes conditional independence graphs for dense regulatory network recovery. Bioin- formatics 28:2029-2036, PMID: 22685074.

  • Logsdon B., Hoffman G., Mezey J. 2012. Mouse obesity network reconstruction with a variational Bayes algorithm to employ agressive false positive control. BMC Bioinformatics 13:53, PMID: 22471599. - Designated as highly accessed by BMC Bioinformatics

  • Brisbin A., Cruickshank J., Moise N., Gunn T., Milano A., Bustamante C., Mezey J. 2011. Fast, exact linkage analysis for categorical trais on arbitrary pedigree designs. Genetic Epidemiology 35:371-380, PMID: 21520271.

  • Logsdon B., Mezey J. 2010. Gene expression network reconstruction by convex feature selection while incorporating genetic perturbations. PLoS Computational Biology 6:e1001014, PMID: 21152011.

  • Brisbin A., Weissman M., Fyer A., Hamilton S., Knowles J., Bustamante C., Mezey J. 2010. Bayesian linkage analysis of categorical traits for arbitrary pedigree designs. PLoS ONE 5:e12307, PMID: 20865038.

  • Logsdon B., Hoffman G., Mezey J. 2010. A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis. BMC Bioinformatics 11:58, PMID: 20105321.